Appropriateness of Using a Computer Simulation Approach in Evaluating the Efficiency of a Units Dose Drug Distribution System INTRODUCTION An automated unit dose packaging system, Pyxis Oral Solid Packager (POSP, see Figure 1) system, was put into operation in January, 2008 at the Inpatient Pharmacy of Cincinnati Children’s Hospital Medical Center (CCHMC), Cincinnati, Ohio for filling the most-used oral solid doses. The CCHMC pharmacy management wondered if a computer simulation approach could be used to accurately predict the efficiency outcomes of using the POSP system. This study was conducted to determine the appropriateness of using the computer simulation approach in drug distribution system studies. Computer simulation is a process of designing a complex model for a real or proposed working system, and it can be a powerful and flexible tool to evaluate the efficiency of a workflow system. OBJECTIVE · To determ...